Argentina's Diego Schwartzman (pictured left) upset the number five-seeded and 2014 U.S. Open champion, Marin Cilic of Croatia, on Friday in Flushing Meadows, nailing down an unexpected 4-6, 7-5, 7-5, 6-4 victory inside Grandstand.
Schwartzman is playing some of his best tennis in 2017 and has reached the fourth round of a major for the first time in his career.
Awaiting him in the next round is the 16th-seeded Frenchman Lucas Pouille, a 2-6, 6-3, 6-4, 6-4 victor Friday afternoon over Kazahkstan's Mikhail Kukushkin.
Also believing more "newer" faces are coming through, and opportunities opening up for them to reach the latter stages of major tournaments, he says: "I think it's a little bit of a new era with many players, new players".
Schwartzman, 25, broke his opponent nine times, including four times in the third set, to ensure there are no former title winners in the bottom half of the draw and guarantee there will be a first-time US Open finalist.
Canadian teen Denis Shapovalov continued his run in Flushing Meadows, advancing past Kyle Edmund of Great Britain.More news: Super Eagles victory was down to prayers - Governor Udom
On playing Querrey in the fourth round, he said: "I think his backhand is pretty good".
"Every grand slam, it's a chance for young guys to prove themselves and I have been doing that".
Showing his famed batting qualities, he lost the first set to the Croat 6-4, before turning the match round, taking the next two sets 7-5, before completing the win by taking the fourth set 6-4. "Hopefully it's nothing too serious", said Shapovalov.
Shapovalov will play for a quarter-final berth against Spanish 12th seed Pablo Carreno Busta, who ousted French qualifier Nicolas Mahut 6-3, 6-4, 6-3. Lorenzi scored an upset win over 19th seed Gilles Muller in four tight sets en route the fourth round.
World number one Rafael Nadal, all-time Grand Slam victor Roger Federer, Austrian Dominic Thiem and Belgium's David Goffin are the only players ranked in the top 10 that remain in NY.
Baby news from Florida turned heads at the year's final Grand Slam event as Williams, a 23-time Grand Slam champion, gave birth to the child she was pregnant with when she won the Australian Open in January.More news: Kejriwal slams MCD, calls Ghazipur landfill collapse man-made disaster
The elder of the Williams sisters was delighted to hear of the news, saying: "Obviously, I'm super-excited".
Whoever triumphs in that matchup has a hard fourth-round fixture on their hands, though, with the victor of Caroline Garcia and Petra Kvitova's meeting up next. "Words can't describe it".
The 13th-seeded Kvitova is in the fourth round at Flushing Meadows for the third time in a row.
It was only the 19th match of the year for Kvitova, who missed the first half of the season after she was cut on her left hand - the one she holds her racket with - during an attack by a knife-wielding intruder at her home in the Czech Republic in December.
Five women still remain in contention for the No. 1 ranking as the U.S. Open's third round begins. Only current number one Karolina Pliskova and fourth-seeded Elina Svitolina could deny her reaching the top for the first time.
Russian wildcard Maria Sharapova was victorious in the last match of the day, defeating fellow wildcard Sofia Kenin in straight sets to set up a last 16 clash against last year's quarter-finalist, Anastasija Sevastova.More news: Andrew Luck 'unlikely' to play Week 1
Sharapova, the 2006 US Open victor, has already beaten Halep and Hungary's Timea Babos in her first Grand Slam since serving a 15-month doping ban after testing positive for the blood booster meldonium, at the 2016 Australian Open.
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