Giroud has been able to muscle Alvaro Morata out of Antonio Conte's plans, with a proven Premier League performer being favoured to a £70 million signing.
Salah was given a chance to impress in Chelsea's home clash with Norwich City towards the end of the season but Mourinho made a decision to haul his January signing off at the break after a subdued first half. Chelsea will have a boost with Marcos Alonso coming back after a three game suspension.
The spotlight at Stamford Bridge was on league top scorer Mohamed Salah, facing his old club, but the Egypt forward was booked for diving and had a quiet afternoon - one that was understandable in the circumstances, according to Klopp.More news: Rohit, Pandya bros take Mumbai home
Salah was hauled off at half-time in Chelsea's 0-0 draw with Norwich City.
Blues boss Conte said: "In the league, you have 38 games to show you deserve to win the league, to show you are the best during the season".
"We have 11 or 12 players that have been playing constantly, so now we have one full week [before the next game] and that helps massively". But first the Reds have to ensure they feature in next season's Champions League.More news: Commerce, Cloud Computing Drove Alibaba Group Holding Ltd (BABA) Earnings Higher
The result means Liverpool now need a win against Brighton and Hove Albion on the final day of the Premier League season to finish in the top four and guarantee a spot in next season's Champions League regardless of the result of this month's final against Real Madrid.
Chelsea have two more games to play with maximum points needed at home to Huddersfield on Wednesday. Attention to detail will be hugely important if Chelsea want to get anything from this match, with Conte highlighting the explosiveness of Salah, Mané and Firmino, together with the opportunities they can create in behind.
Liverpool manager Juergen Klopp handed fullback Nathaniel Clyne a rare start, with Trent Alexander-Arnold moving into midfield, while there was no Alvaro Morata for Chelsea.More news: Toure to leave Manchester City at the end of the season
For Chelsea, David Luiz and Ethan Ampadu are out, with both sustaining long-term injuries. We should see Bakayoko starting, together with Olivier Giroud, in a mission to exploit Liverpool's defensive fragilities.
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