Messi's Argentina, however, were unable to quell a rampant France side who had finally found their feet at the World Cup and could only watch as Kylian Mbappe scored two goals in an eventual 4-3 thriller of a win.
Ronaldo, who will be 37 by the time of the next World Cup, was unable to keep Portugal alive despite incessant pressure from his side in the dying stages of the match.More news: Drake confirms he secretly fathered a son on new album 'Scorpion'
Edinson Cavani, who failed to finish the match after suffering a late injury, scored a superb goal in each half, and although Pepe scored in-between, it was not enough to halt the Uruguayans, who have now won all four of their matches so far in Russian Federation.
Portugal coach Fernando Santos threw up his hands in disgust, realising that coming from behind a second time against this Uruguay defence was going to be a tall order.
"I am sure that Portugal will continue to be one of the best teams in the world".More news: Serbia 0 - 2 Brazil - Match Report & Highlights
Many praised Ronaldo for an apparent act of sportsmanship.
By that time, Ronaldo's situation at club level will be clearer after he raised doubts about his future with Real Madrid in the wake of their Champions League final win against Liverpool in May.
Former Argentina footballer Diego Maradona on Friday praised the former Brazil worldwide Ronaldo and said he would have been the best player ever if his career was not hindered by injuries.More news: Southgate urges England to play Belgium without fear
FIFA has now commented on the situation by providing support for a player widely regarded to be one of the greatest ever, urged the 57-year-old - part of the FIFA Legends Program - to be respectful.
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